Message-ID: <0B858112-7EB6-4A52-8A92-1C776FD65B43@ucr.edu>
Date: 2019-03-22T16:31:28Z
From: Luke Klein
Subject: [Bioc-devel] Call for collaborators/advice
I am writing a package that will extend the GenomicInteractions class. I am a statistician, so I may not know best practices when it comes to extending existing classes (eg. should I make a new slot or simply add a column to the `elementMetadata`? Are there existing functions that already do what I am attempting?).
I am not familiar with Bioc-Devel decorum, so if asking this here is inappropriate, kindly let me know.
About my project:
In the first step, I am hoping to implement a HiC binning function on HiC data contained in a GenomicInteractions set. I aim to:
- Reorder the anchor pairs (I will explain in more detail to anyone that wants to help)
- Collapse the regions to the desires bin width
- Sum the counts within each bin
- Update the anchors to agree with the new/updated regions
This will set the stage for the new class that I hope to create for HiC domain calling, but I need to achieve the above tasks first.
All the best to everyone!
? Luke Klein
PhD Student
Department of Statistics
University of California, Riverside
lklei001 at ucr.edu
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