On Mar 22, 2019, at 2:44 PM, Kasper Daniel Hansen <kasperdanielhansen at gmail.com> wrote:
Why is this not "just" a function which transforms one GI into another GI?
Thats what it seems to me.
On Fri, Mar 22, 2019 at 12:31 PM Luke Klein <lklei001 at ucr.edu> wrote:
I am writing a package that will extend the GenomicInteractions class. I
am a statistician, so I may not know best practices when it comes to
extending existing classes (eg. should I make a new slot or simply add a
column to the `elementMetadata`? Are there existing functions that already
do what I am attempting?).
I am not familiar with Bioc-Devel decorum, so if asking this here is
inappropriate, kindly let me know.
About my project:
In the first step, I am hoping to implement a HiC binning function on HiC
data contained in a GenomicInteractions set. I aim to:
- Reorder the anchor pairs (I will explain in more detail to
anyone that wants to help)
- Collapse the regions to the desires bin width
- Sum the counts within each bin
- Update the anchors to agree with the new/updated regions
This will set the stage for the new class that I hope to create for HiC
domain calling, but I need to achieve the above tasks first.
All the best to everyone!
? Luke Klein
PhD Student
Department of Statistics
University of California, Riverside
lklei001 at ucr.edu
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