[Bioc-devel] biocViews and DNA-methylation
On Tue, Jul 29, 2008 at 2:24 PM, mattia pelizzola
<mattia.pelizzola at gmail.com> wrote:
Hi, I'm going to submit to Bioconductor a package for the estimation of absolute and relative DNA-methylation levels from MeDIP enrichment measures. MeDIP is a methodology based on an antibody specific for 5-methyl-Cytosines (Weber et al, 2005). I'm confused about the choice of the biocViews terms. The library has been developed based on MeDIP-enrichment measures derived from two-channel arrays. Nevertheless, there are people working with it with enrichment measures determined by one-channel technologies. Moreover, the library is not strictly dependent on microarray data. Even next gen sequencing data could be potentially suitable. All that is necessary is enrichment measures associated with genomic positions. For these reason I do not know if to choose any of the terms related to microarray. Also Microarray/CpGIsland is not really appropriate. Maybe Technology/Genetics. Is it finally necessary to add new term(s) related with epigenetics / DNA-methylation?
Hi, Mattia. I would include all the terms that might be relevant. That said, we could consider adding terms for epigenetics or dna methylation. Sean