It seems to me we may need a class to manage related annotation
structures. For example, the chromImpute segmentations of the genome
defined for various cell types. I would like to be able to take a region
of the genome (say a SNP) and ask how the state varies across cell types.
AnnotationHub will provide access to cell-type specific GRanges but there
is no container that I can think of that would coordinate these as analogous
to different "samples".
Am I missing something?