[Bioc-devel] RFC: eSet with two color data
"Simon Lin" <simonlin at duke.edu> writes:
I would also like to bring the attention to another single color platform, beadArray (by Illumina). It sounds less complex (single color), but has more measurements (other than intensity) for each gene (more exactly, oligo reporter): for example, number of beads, and standard deviation of on-the-array technical replicates. We did model it in the lumi package, but we would certainly like to make the design more consistent with other packages.
I think that in the case of a BeadArraySet, that ExpressionSet is more directly applicable. If I understand your discription and based on the code in the lumi package, you need more matrices conformant to exprs but with different data, but don't have different phenoData for each matrix type. There is similar code in the beadarray package. I would like to see collaboration with Mark Dunning in any discussion of a more formal BeadArraySet definition. Best Wishes, + seth
Seth Falcon | Computational Biology | Fred Hutchinson Cancer Research Center http://bioconductor.org