Hi, this is a kind request for the BioC team to have another look at fixing the binary affxparser builds. Quite a few OSX users on R v2.14.0 have R crashing because of this problem. Since thread 'Re: [Bioc-devel] affxparser: Core dump with R 2.14.0 on OSX' on Nov 7, 2011 [https://stat.ethz.ch/pipermail/bioc-devel/2011-November/002969.html] became cluttered with mistakes, I'm starting a new thread on the same topic. PROBLEM: The binary build of affxparser v1.26.2 for OSX provided by Bioconductor is broken and causes R v2.14.0 to crash ("core dump", "abort trap", ...) on OSX 10.6 ("Snow Leopard") and (I assume; someone please confirm) OSX 10.7 ("Lion"), but not OSX 10.5 ("Leopard"). A reproducible example is: library("affxparser"); readCdfHeader("Mapping10K_Xba142.cdf"); which should return a named header. (Download CDF file: http://www.aroma-project.org/data/annotationData/chipTypes/Mapping10K_Xba142/Mapping10K_Xba142.CDF.gz ; 2.2Mb). Another example is [http://www.aroma-project.org/data/annotationData/chipTypes/Mapping250K_Nsp/Mapping250K_Nsp.cdf.gz]: library("affxparser"); readCdfHeader("Mapping250K_Nsp.cdf"); CURRENT WORKAROUNDS: - Install affxparser from source [http://bioconductor.org/packages/2.9/bioc/src/contrib/affxparser_1.26.2.tar.gz]. - Install Kasper Hansen's binary build (not universal?) [http://www.braju.com/R/repos/osx_10.6/affxparser_1.26.2.tgz] that works on (at least) OSX 10.6.8. See also aroma.affymetrix thread 'OSX 10.6 & 10.7 users: Workaround for faulty BioC build of affxparser v1.26.2' on Jan 14, 2012 [https://groups.google.com/forum/#!topic/aroma-affymetrix/lEfDanThLEA/discussion] TROUBLESHOOTING: I can confirm that installing from source, works on an OSX 10.6.8 machine with R v2.14.1 (http://cran.r-project.org/bin/macosx/R-2.14.1.pkg). Installing Kasper's binary build also works. I've a limited understanding on the different types of OSX package binaries, only access to OSX 10.6.8, making it hard for me to do any more troubleshooting, but as far as I understand there is something wrong with the way affxparser is build on the Bioconductor servers. Thanks Henrik
[Bioc-devel] affxparser: Core dump with R 2.14.x on OSX [take #2]
1 message · Henrik Bengtsson