Hi, I've identified a few missing PWMs from the MotifDb package and would like to help get them added. I posted on the support page but have not received a response after 10 days, so messaging here instead (link to forum post: https://support.bioconductor.org/p/131312/). Full details can be found in the support post, but in summary, there are a small number of Drosophila transcription factors which do not have any entries in MotifDb, meaning anyone using that database for their motif analysis will not identify these factors as potential candidates. A .meme format file ("flyFactor_Missing_Motifdb.meme") of these missing motifs along with a reproducible script to identify these factors can be found at this gist: https://gist.github.com/snystrom/b7701858bec6bc4ce7758a7582422359. I am happy to help curate any additional metadata required to get these factors added to the database. Best, -Spencer
[Bioc-devel] MotifDb missing some PWMs from FlyFactorSurvey database
4 messages · Nystrom, Spencer, Paul Shannon, Shepherd, Lori
Thanks, Spencer. Sorry I missed the support posting - there?s no automatic forwarding from there to maintainers. I?ll take a look at this later today, then post back to the support list, and we will get a fix in. Thank you for pointing out the problem! - Paul
On Jun 5, 2020, at 9:46 AM, Nystrom, Spencer <snystrom at email.unc.edu> wrote: Hi, I've identified a few missing PWMs from the MotifDb package and would like to help get them added. I posted on the support page but have not received a response after 10 days, so messaging here instead (link to forum post: https://support.bioconductor.org/p/131312/). Full details can be found in the support post, but in summary, there are a small number of Drosophila transcription factors which do not have any entries in MotifDb, meaning anyone using that database for their motif analysis will not identify these factors as potential candidates. A .meme format file ("flyFactor_Missing_Motifdb.meme") of these missing motifs along with a reproducible script to identify these factors can be found at this gist: https://gist.github.com/snystrom/b7701858bec6bc4ce7758a7582422359. I am happy to help curate any additional metadata required to get these factors added to the database. Best, -Spencer [[alternative HTML version deleted]]
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Paul - On the support site, you can edit your profile and put package names as watchedtags. When a person posts to the support site and tags with the package name you would then be emailed. This assumes they tag the post correctly but also an option Lori Shepherd Bioconductor Core Team Roswell Park Comprehensive Cancer Center Department of Biostatistics & Bioinformatics Elm & Carlton Streets Buffalo, New York 14263
From: Bioc-devel <bioc-devel-bounces at r-project.org> on behalf of Paul Shannon <paul.thurmond.shannon at gmail.com>
Sent: Friday, June 5, 2020 1:12 PM
To: Nystrom, Spencer <snystrom at email.unc.edu>
Cc: bioc-devel at r-project.org <bioc-devel at r-project.org>
Subject: Re: [Bioc-devel] MotifDb missing some PWMs from FlyFactorSurvey database
Sent: Friday, June 5, 2020 1:12 PM
To: Nystrom, Spencer <snystrom at email.unc.edu>
Cc: bioc-devel at r-project.org <bioc-devel at r-project.org>
Subject: Re: [Bioc-devel] MotifDb missing some PWMs from FlyFactorSurvey database
Thanks, Spencer. Sorry I missed the support posting - there?s no automatic forwarding from there to maintainers. I?ll take a look at this later today, then post back to the support list, and we will get a fix in. Thank you for pointing out the problem! - Paul > On Jun 5, 2020, at 9:46 AM, Nystrom, Spencer <snystrom at email.unc.edu> wrote: > > Hi, > > I've identified a few missing PWMs from the MotifDb package and would like to help get them added. I posted on the support page but have not received a response after 10 days, so messaging here instead (link to forum post: https://secure-web.cisco.com/1TFAehHIfvF8C-fsHqKF9EZUlEaLQqYsIygNO_BAsoXZwv_Wu3u5B4wJVetP6b2oLhIIOFSZhhOumdKzED0ovgHBPNyPVtPXiHxRm8b66_DTxd3gOar2MNQ5l9qQH4_wqJMMJaxbnBCWUwAGnSDJO91ueABvVc6mU2FAghpGjUfBlWvlYMMhZzzmbgjYqsldl1Ta23cGowoJ3ncf7CeSKr6bKFMch5qHT0BqRq0t6Gi_b7w1KzlscAc0wC3Pxjq5gXX9vMchpSqTrtO3_MRw3Ojfo2wOimSuSsQL0RWe2mKIGnuSE0r8q7XSF0fsyFaH-DmeMbMdAxJok14mifZioaA/https%3A%2F%2Fsupport.bioconductor.org%2Fp%2F131312%2F). Full details can be found in the support post, but in summary, there are a small number of Drosophila transcription factors which do not have any entries in MotifDb, meaning anyone using that database for their motif analysis will not identify these factors as potential candidates. A .meme format file ("flyFactor_Missing_Motifdb.meme") of these missing motifs along with a reproducible script to identify these factors can be found at this gist: https://secure-web.cisco.com/1Hw4j-u2eWVf5hZXzqLZ4apPGgjUddOX5ixtNdTGwQZ4NPy_KaMZids5AaShi-S2meTRVKS9jM3cf2iEulIctx81-ZyEXDGgnDv79mSzGZG0QjWEwCoKwaCa8Eg2m1zL4AW14psIhbcmvxc36OZX77cPdvVBZBl0WIzqa0g6N2n6c75iPRS0Mi4k86awArVwZ6SMWbd9onXyqHQqqfNpEcQnilZw0UkOntlEVSBQWpNszEdDH6zw1gLuglq1F4JIJwa6onOYuveddTXIVT0r3veLCqhDXiDZIxFN9PmMrUUh9Xqiq2S2uRkK53JqfA-krBLQfCwo4agchyGpfqwWZOA/https%3A%2F%2Fgist.github.com%2Fsnystrom%2Fb7701858bec6bc4ce7758a7582422359. I am happy to help curate any additional metadata required to get these factors added to the database. > > Best, > -Spencer > > [[alternative HTML version deleted]] > > _______________________________________________ > Bioc-devel at r-project.org mailing list > https://secure-web.cisco.com/1phkYo14BRVEEfRyDeaWIrA_pTixsBkMhDEtZJJ_lcV4Ev3nOgpobNwVMNGC0rZ2PP6k0_GxcU4pZuXfj6Z7QQPVun1pslCmmsy8p06Qu26qc8oyiqhJjbddn3W2_2Ob0TkyCNLtOmsOod2iPUdW5HOZnOD8E-hbZEtkd686fRcOfBp0Jol1LdMws-yzTnx2tiY_wuC1fknOPQLjJGju7wMdRHS7Gs1hBT2TcDXo-S2HFRYoKlUZ3TdrVjREc1Lkb0Ik_wRG32UHcv2ZJFMDBlzvcGyI7wY1ihTeNfIGgVPAumaUWOyPKVVFnWC990wgBf1-PbTrIFFfwRUZhaHpnQw/https%3A%2F%2Fstat.ethz.ch%2Fmailman%2Flistinfo%2Fbioc-devel _______________________________________________ Bioc-devel at r-project.org mailing list https://secure-web.cisco.com/1phkYo14BRVEEfRyDeaWIrA_pTixsBkMhDEtZJJ_lcV4Ev3nOgpobNwVMNGC0rZ2PP6k0_GxcU4pZuXfj6Z7QQPVun1pslCmmsy8p06Qu26qc8oyiqhJjbddn3W2_2Ob0TkyCNLtOmsOod2iPUdW5HOZnOD8E-hbZEtkd686fRcOfBp0Jol1LdMws-yzTnx2tiY_wuC1fknOPQLjJGju7wMdRHS7Gs1hBT2TcDXo-S2HFRYoKlUZ3TdrVjREc1Lkb0Ik_wRG32UHcv2ZJFMDBlzvcGyI7wY1ihTeNfIGgVPAumaUWOyPKVVFnWC990wgBf1-PbTrIFFfwRUZhaHpnQw/https%3A%2F%2Fstat.ethz.ch%2Fmailman%2Flistinfo%2Fbioc-devel This email message may contain legally privileged and/or confidential information. If you are not the intended recipient(s), or the employee or agent responsible for the delivery of this message to the intended recipient(s), you are hereby notified that any disclosure, copying, distribution, or use of this email message is prohibited. If you have received this message in error, please notify the sender immediately by e-mail and delete this email message from your computer. Thank you.
Hi Lori, Excellent solution. I will update my profile. Thank you! (I should have guessed bioc would have a mechanism for this)
On Jun 5, 2020, at 10:16 AM, Shepherd, Lori <Lori.Shepherd at RoswellPark.org> wrote: Paul - On the support site, you can edit your profile and put package names as watchedtags. When a person posts to the support site and tags with the package name you would then be emailed. This assumes they tag the post correctly but also an option Lori Shepherd Bioconductor Core Team Roswell Park Comprehensive Cancer Center Department of Biostatistics & Bioinformatics Elm & Carlton Streets Buffalo, New York 14263 From: Bioc-devel <bioc-devel-bounces at r-project.org> on behalf of Paul Shannon <paul.thurmond.shannon at gmail.com> Sent: Friday, June 5, 2020 1:12 PM To: Nystrom, Spencer <snystrom at email.unc.edu> Cc: bioc-devel at r-project.org <bioc-devel at r-project.org> Subject: Re: [Bioc-devel] MotifDb missing some PWMs from FlyFactorSurvey database Thanks, Spencer. Sorry I missed the support posting - there?s no automatic forwarding from there to maintainers. I?ll take a look at this later today, then post back to the support list, and we will get a fix in. Thank you for pointing out the problem! - Paul
On Jun 5, 2020, at 9:46 AM, Nystrom, Spencer <snystrom at email.unc.edu> wrote: Hi, I've identified a few missing PWMs from the MotifDb package and would like to help get them added. I posted on the support page but have not received a response after 10 days, so messaging here instead (link to forum post: https://secure-web.cisco.com/1TFAehHIfvF8C-fsHqKF9EZUlEaLQqYsIygNO_BAsoXZwv_Wu3u5B4wJVetP6b2oLhIIOFSZhhOumdKzED0ovgHBPNyPVtPXiHxRm8b66_DTxd3gOar2MNQ5l9qQH4_wqJMMJaxbnBCWUwAGnSDJO91ueABvVc6mU2FAghpGjUfBlWvlYMMhZzzmbgjYqsldl1Ta23cGowoJ3ncf7CeSKr6bKFMch5qHT0BqRq0t6Gi_b7w1KzlscAc0wC3Pxjq5gXX9vMchpSqTrtO3_MRw3Ojfo2wOimSuSsQL0RWe2mKIGnuSE0r8q7XSF0fsyFaH-DmeMbMdAxJok14mifZioaA/https%3A%2F%2Fsupport.bioconductor.org%2Fp%2F131312%2F). Full details can be found in the support post, but in summary, there are a small number of Drosophila transcription factors which do not have any entries in MotifDb, meaning anyone using that database for their motif analysis will not identify these factors as potential candidates. A .meme format file ("flyFactor_Missing_Motifdb.meme") of these missing motifs along with a reproducible script to identify these factors can be found at this gist: https://secure-web.cisco.com/1Hw4j-u2eWVf5hZXzqLZ4apPGgjUddOX5ixtNdTGwQZ4NPy_KaMZids5AaShi-S2meTRVKS9jM3cf2iEulIctx81-ZyEXDGgnDv79mSzGZG0QjWEwCoKwaCa8Eg2m1zL4AW14psIhbcmvxc36OZX77cPdvVBZBl0WIzqa0g6N2n6c75iPRS0Mi4k86awArVwZ6SMWbd9onXyqHQqqfNpEcQnilZw0UkOntlEVSBQWpNszEdDH6zw1gLuglq1F4JIJwa6onOYuveddTXIVT0r3veLCqhDXiDZIxFN9PmMrUUh9Xqiq2S2uRkK53JqfA-krBLQfCwo4agchyGpfqwWZOA/https%3A%2F%2Fgist.github.com%2Fsnystrom%2Fb7701858bec6bc4ce7758a7582422359. I am happy to help curate any additional metadata required to get these factors added to the database. Best, -Spencer [[alternative HTML version deleted]]
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