fisher.test() in ctest or perhaps uniroot() (PR#455)

thomas@biostat.washington.edu writes:

fisher.test(matrix(c(1,20,246,6873),2),hybrid=F)
Error in if (f(lower, ...) * f(upper, ...) >= 0) stop("f() values at end
points not of opposite sign") :
        missing value where logical needed

Problem seems to be that mnhyper as defined doesn't like extreme
arguments, and is being called with

 1/.Machine$double.eps

e.g.

get("mnhyper",envir=DUMP$sys.frames[[2]])(1000000000000000)

[1] NaN

get("mnhyper",envir=DUMP$sys.frames[[2]])(100000000000000)

[1] 21

The code looks like this:

    if (ncp == 0) 
        return(lo)
    if (ncp == Inf) 
        return(hi)
    q <- lo:hi
    d <- dhyper(q, m, n, k) * ncp^(0:(hi - lo))

And I suspect that the test should be ncp^(hi-lo)==Inf.

Seems to work:

fisher.test(matrix(c(1,20,246,6873),2),hybrid=F)

Fisher's Exact Test for Count Data 

data:  matrix(c(1, 20, 246, 6873), 2) 
p-value = 0.5231 
alternative hypothesis: true odds ratio is not equal to 1 
95 percent confidence interval:
 0.0335691 8.8064130 
sample estimates:
odds ratio 
  1.396855

O__  ---- Peter Dalgaard             Blegdamsvej 3  
  c/ /'_ --- Dept. of Biostatistics     2200 Cph. N   
 (*) \(*) -- University of Copenhagen   Denmark      Ph: (+45) 35327918
~~~~~~~~~~ - (p.dalgaard@biostat.ku.dk)             FAX: (+45) 35327907
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