Nesting order for mixed models
On Tue, Mar 10, 2009 at 2:47 PM, Jon Zadra <jrz9f at virginia.edu> wrote:
Hello,
I am confused about the order of nesting in mixed models using functions like aov(), lme(), lmer().
I have the following data:
n subjects in either condition A or B
each subject tested at each of 3 numerical values ("distance" = 40,50,60),
repeated 4 times for each of the 3 numerical values ("trial" = 1,2,3,4)
Variable summary: Condition: 2 level factor Distance: numerical (but only 3 values) in the same units as "y" Trial: 4 level factor
I don't think Trial is necessary. If I understand correctly it is not really an experimental or observational factor in that you don't expect that trial 1 for one subject/distance combination will be related to trial 1 for another combination.
I expect the subjects' data to differ due to condition and distance, and am doing repeated measurements to reduce any variability due to measurement error. Currently I'm using this model: lme(y ~ Condition + Distance, random = ...) the question is how do I organize the random statement? ?Is it: random = ~1 | Subject
I think that is all you need. In lmer the formula would be y ~ Condition + Distance + (1|Subject).
random = ~1 | Subject/Trial random = ~1 | Trial/Subject random = ~1 | Condition/Distance/Subject/Trial ...etc, or something else entirely? Mostly I'm unclear about whether the Trials should be grouped under subject because I expect the trials to be more similar within a subject than across subjects, or whether subjects should be grouped under trials because the trials are going to differ depending on the subject. ?If trials should be grouped under subjects, then do the condition or distance belong as well, since the trials will be most similar within each distance within each subject?
In some ways of thinking of the model, Trial would be grouped under the Subject:Distance combination but then it becomes unnecessary because it is just another way of labeling the observations. A random effect for Trial within Subject:Distance is confounded with the "residual" or per-observation noise term.