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Tools for data preparation?

My choices are (in the order of my preference):

- use connections and readLines()/strsplit()/etc. in R to process the file a
chunk at a time

- use cut/paste/grep/etc., perhaps within pipe() in R

- use awk, perhaps within pipe() in R

- Python is my last resort, as I'm not familiar with it

The first preference is to do it all in R, mostly for the reason that I can
keep track of what was done all in one place (the R script or function).

Andy