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M value and fold change

solie.alizadeh at utoronto.ca 
Hi everyone,

I have a question about M value and how it corresponds to gene  
expression fold change.I was wondering if for example M-value of -1.27  
which means 0.41 in fold change, doesn it mean 0.41 of the control (in  
my experiment wild type? Better say does it mean this gene is  
down-regulated by 41% or 59% (1-41)? I was abit confused about it. I  
appreciate if anyone can help me to figure this out.

Thanks in Advance,
Solmaz Alizadeh