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Reading large files in R

... and it is likely that even if you did have enough memory (several times
the size of the data are generally needed) it would take a very long time.

If you do have enough memory and the data are all of one type -- numeric
here -- you're better off treating it as a matrix rather than converting it
to a data frame.

-- Bert Gunter
Genentech Non-Clinical Statistics
South San Francisco, CA
 
"The business of the statistician is to catalyze the scientific learning
process."  - George E. P. Box