Message-ID: <43E21988.4090805@bioassay.dk>
Date: 2006-02-02T14:39:04Z
From: Christian Ritz
Subject: calculating IC50
In-Reply-To: <39B6DDB9048D0F4DAD42CB26AAFF0AFAFED7AF@usctmx1106.merck.com>
Hi!
Yes, the 'drc' package can be used to obtain IC50 or any other ICx value
for several, commonly used dose-response models.
The vignette is more up-to-date than the article in JSS (which dates
back to the start of 2005).
Christian
Liaw, Andy wrote:
>Perhaps also of interest is the `drc' package on CRAN. There's an article
>in JSS describing it (probably the same as the package vignette--- haven't
>checked).
>
>Andy
>
>From: Prof Brian Ripley
>
>
>>On Thu, 2 Feb 2006 Arne.Muller at sanofi-aventis.com wrote:
>>
>>
>>
>>>I was wondering if there is an R-package to automatically
>>>
>>>
>>calculate the
>>
>>
>>>IC50 value (concentration of a substrance that inhibits
>>>
>>>
>>cell growth to
>>
>>
>>>50%) for some measurements.
>>>
>>>
>>Function dose.p in recommended package MASS.
>>
>>--
>>Brian D. Ripley, ripley at stats.ox.ac.uk
>>Professor of Applied Statistics, http://www.stats.ox.ac.uk/~ripley/
>>University of Oxford, Tel: +44 1865 272861 (self)
>>1 South Parks Road, +44 1865 272866 (PA)
>>Oxford OX1 3TG, UK Fax: +44 1865 272595
>>
>>______________________________________________
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>>
>>
>>
>>
>
>______________________________________________
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>
>