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What is c1 file and how to open it (.c1) in R program?

That was a bit too long for a fortune nomination. Jeff, perhaps you can tighten it up a bit and resubmit?  I can observe that with my Bayesian wetware and Google, the highest posterior was for these files to be in the CEL format. However the best place to have posted this would have been on the Bioconductor support webpage.

Su Yon; When you do follow Jeff's sensible advice to post to the Bioc page at https://support.bioconductor.org/ be sure to follow the rest of his advice to offer more specifics, including a text representation of the first few lines or better details on the creator of these files.

( I tried a search on that website but '.c1' is just not narrow enough and adding "genetic" on  Bioconductor search string would have minimal narrowing consequences. )