Enormous Datasets

Dear List,
I have some projects where I use enormous datasets.  For instance, the 5% PUMS microdata from the Census Bureau.  After deleting cases I may have a dataset with 7 million+ rows and 50+ columns.  Will R handle a datafile of this size?  If so, how?

Thank you in advance,
Tom Volscho

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Thomas W. Volscho
Graduate Student
Dept. of Sociology U-2068
University of Connecticut
Storrs, CT 06269
Phone: (860) 486-3882
http://vm.uconn.edu/~twv00001