Manly's randomization analysis of multiple regression

My wife has been using a diagnostic from Manley (1991; "Randomization and MonteCarlo Methods in Biology") that compares a normal multiple regression's performance with that using random predicted variables. 

Is there something like this already available in R? 

If not, the "boot" package looks like a good place to start looking for methods, no?

Thanks in advance 
Bruce L.