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Message-ID: <8E0FD6416F30784B96DDB809F794F13109290CCB@rie-ex1.luht.scot.nhs.uk>
Date: 2009-11-09T09:44:57Z
From: McAllister, David
Subject: ImproveProb Function in Design Package

Hello

Thanks to Frank Harrell for the great Design package. I noted from Pencina's Article (Statistics in Medicine Vol 27, pp157-172) that the result obtained for the Net Reclassification Index depends upon categorical cut-offs for risk (eg in the paper <6%, 6-20% and >20%). I wondered how the improveprob function arrives at its cut-offs, and whether there was any function to change the default cut-offs used.

Thanks for any help you can offer.

Yours sincerely

David McAllister


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