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are R packages safe?

On the plus side, all binary packages on CRAN are built from source code automatically by the CRAN team, so it would be a bit audacious to include "unsafe" code when the source code had to reviewable at any time.

There is nothing in R that would prevent a user from downloading a binary package from a non-CRAN source, though.

The only legally defensible answer is No, you use this at your own risk.