sib TDT transmission/disequilibrium test
"Farrel Buchinsky" <fjbuch at gmail.com> wrote:
Does anyone know if the sib TDT has been implemented in R 1. Spielman, R.S., and Ewens, W.J. (1998) A sibship test for linkage in the presence of association: the sib transmission/disequilibrium test. Am J Hum Genet 62, 450-458
It can be done as a conditional logistic regression (look at clogit). I don't think the sib TDT is as efficient as an FBAT approach, which can be applied to that type of data. David Duffy. | David Duffy (MBBS PhD) ,-_|\ | email: davidD at qimr.edu.au ph: INT+61+7+3362-0217 fax: -0101 / * | Epidemiology Unit, Queensland Institute of Medical Research \_,-._/ | 300 Herston Rd, Brisbane, Queensland 4029, Australia GPG 4D0B994A v