Message-ID: <1345765975.29604.YahooMailNeo@web142602.mail.bf1.yahoo.com>
Date: 2012-08-23T23:52:55Z
From: arun
Subject: Please help....normalization by the median of some control genes
In-Reply-To: <1345725474.91044.YahooMailNeo@web113508.mail.gq1.yahoo.com>
HI,
You could try:
limma package: normalizeWithinArrays()
A.K.
----- Original Message -----
From: David Lyon <david_lyon3 at yahoo.com>
To: "r-help at r-project.org" <r-help at r-project.org>
Cc:
Sent: Thursday, August 23, 2012 8:37 AM
Subject: [R] Please help....normalization by the median of some control genes
Can someone show me some code to do normalization by the median of some control genes for the example below?
Many Many Thanks in advance
This strategy selects a subset of genes (called ?control genes?) and makes the median of their data distribution similar across arrays.
??? ??? id1??? id2??? id3
control1??? 0.8??? 0.7??? 0.6
control2??? 0.6??? 0.2??? 0.4
probe1??? ??? 0.3??? 0.2??? 0.5
probe2??? ??? 0.4??? 0.9??? 0.7
probe3??? ??? 0.6??? 0.7??? 0.4
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