gsDesign

I'm trying to use gsDesign for a noninferiority trial with binary
endpoint. Did anyone know how to specify the trial with different sample
sizes for two treatment groups? Thanks in advance!

Hi,

Presuming that you are using the nBinomial() function, see the 'ratio' argument, which defines the desired sample size ratio between the two groups.

See ?nBinomial and the examples there, which does include one using the 'ratio' argument.

HTH,

Marc Schwartz