Message-ID: <loom.20090228T173917-732@post.gmane.org>
Date: 2009-02-28T17:41:11Z
From: Dieter Menne
Subject: Adjusting confidence intervals for paired t-tests of multiple endpoints
Erich Studerus <erich.studerus <at> bli.uzh.ch> writes:
>
>
> Dear R-users,
>
> In a randomized placebo-controlled within-subject design, subjects recieved
> a psycho-active drug and placebo. Subjects filled out a questionnaire
> containing 15 scales on four different time points after drug
> administration. In order to detect drug effects on each time point, I
> compared scale values between placebo and drug for all time conditions and
> scales, which sums up to 4*15=60 comparisons.
>
....
> Now, I want to adjust the confidence intervals for multiple comparisons.
For simple cases, see p.adjust or TukeyHSD (more limited).
For complex cases, see simint and friends in package multcomp.
Dieter