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why use profile likelihood for Box Cox transformation?

"Paul Livingstone" <paul.livingstone at aerostructures.com.au> writes:
Correct.
This is sort of similar to the issue of output least squares vs.
system least squares in inverse problems theory. 

If what you have is a relation between Y and x and (only) Y is
measured with errors, you'd be getting a bias towards zero in the
estimated B by using the "shuffled" equation.

Then again, it's not really obvious that Box-Cox is right either
because it mixes up the functional relation and the error
chacteristics. Y^lambda should be linear in X _and_ have normally
distributed errors with a constant variance. You might need one lambda
to linearize and another to stabilize the variance.
 
If the errors really enter at the systems level (you have a stochastic
differential equation), it's a different story altogether!