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metafor - multivariate analysis

Dear Owen,

What is your definition of "multivariate analysis"? Do you mean: A meta-regression model with more than one predictor/moderator? In that case, yes, metafor handles that. Usually, this is referred to as "multiple regression" (as opposed to "simple regression" with a single predictor) -- and in the case of a meta-analysis, I guess one could call it "multiple meta-regression". 

If you are referring to a model that handles statistical dependencies in the observed outcomes (and hence requires multivariate methods), then you will have to use some other package (e.g., mvmeta).

See also:

http://stats.stackexchange.com/questions/2358/explain-the-difference-between-multiple-regression-and-multivariate-regression

Best,
Wolfgang