Chi-Square test and survey results

An organization has asked me to comment on the validity of their
recent all-employee survey.  Survey responses, by geographic region, compared
with the total number of employees in each region, were as follows:

ByRegion

          All.Employees Survey.Respondents
Region_1            735                142
Region_2            500                 83
Region_3            897                 78
Region_4            717                133
Region_5            167                 48
Region_6            309                  0
Region_7            806                125
Region_8            627                122
Region_9            858                177
Region_10           851                160
Region_11           336                 52
Region_12          1823                312
Region_13            80                  9
Region_14           774                121
Region_15           561                 24
Region_16           834                134

How well does the survey represent the employee population?
Chi-square test says, not very well:

chisq.test(ByRegion)

        Pearson's Chi-squared test

data:  ByRegion
X-squared = 163.6869, df = 15, p-value < 2.2e-16

By striking three under-represented regions (3,6, and 15), we get
a more reasonable, although still not convincing, result:

chisq.test(ByRegion[setdiff(1:16,c(3,6,15)),])

        Pearson's Chi-squared test

data:  ByRegion[setdiff(1:16, c(3, 6, 15)), ]
X-squared = 22.5643, df = 12, p-value = 0.03166

This poses several questions:

1)  Looking at a side-by-side barchart (proportion of responses vs.
proportion of employees, per region), the pattern of survey responses
appears, visually, to match fairly well the pattern of employees.  Is
this a case where we trust the numbers and not the picture?

2) Part of the problem, ironically, is that there were too many responses
to the survey.  If we had only one-tenth the responses, but in the same
proportions by region, the chi-square statistic would look much better,
(though with a warning about possible inaccuracy):

data:  data.frame(ByRegion$All.Employees, 0.1 *   
(ByRegion$Survey.Respondents))
X-squared = 17.5912, df = 15, p-value = 0.2848

Is there a way of reconciling a large response rate with an unrepresentative
response profile?  Or is the bad news that the survey will give very precise
results about a very ill-specified sub-population?

(Of course, I would put in softer terms, like "you need to assess the degree
of homogeneity across different regions" .)

3) Is Chi-squared really the right measure of how representative is the
survey?

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Thanks for any help you can give - hope these questions make sense -

George H.