Skip to content

lme() with known level-one variances

1 message · Austin, Matt

#
Can you do this using gls() with control = glsControl( sigma = yourValue ) ?

--Matt

-----Original Message-----
From: Thomas Lumley [mailto:tlumley at u.washington.edu]
Sent: Friday, August 30, 2002 9:12 AM
To: Setzer.Woodrow at epamail.epa.gov
Cc: J.R. Lockwood; r-help at stat.math.ethz.ch
Subject: Re: [R] lme() with known level-one variances
On Fri, 30 Aug 2002 Setzer.Woodrow at epamail.epa.gov wrote:

            
That's the problem.

As happens in meta-analysis as well, the problem is to estimate a model
with a variance component fixed. Not fixed up to a scale parameter. Fixed.

In meta-analysis the model is that within each trial a treatment effect
parameter is constant, and as the trial is large the variance of the
estimated treatment effect is very accurately known conditional on the
true treatment effect for that trial. The unconditional variance is then
the known conditional variance plus an unknown variance.

It doesn't seem that lme() is designed for this, and last time I tried to
do it I gave up and changed the model more or less as you suggest.


	-thomas

-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.
-.-
r-help mailing list -- Read http://www.ci.tuwien.ac.at/~hornik/R/R-FAQ.html
Send "info", "help", or "[un]subscribe"
(in the "body", not the subject !)  To: r-help-request at stat.math.ethz.ch
_._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._.
_._
-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-.-
r-help mailing list -- Read http://www.ci.tuwien.ac.at/~hornik/R/R-FAQ.html
Send "info", "help", or "[un]subscribe"
(in the "body", not the subject !)  To: r-help-request at stat.math.ethz.ch
_._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._._