Could anyone help with a linear mixed model fitting problem ? The model is : Y= Xp + Zu + e where X, Z are known design matrix, p is fixed effect factor, u is random effect, u~ (0, G) , e~(0,R) The main problem is , I want to fix the covariance matrix G to be a constant times a known covariance matrix A, G = c*A (c is positive constant, A is a predefined matrix with values manually set by me. I know the correlation option in lme function can specify some kind of correlation. but only with the Construct function defined, not whatever ever form I want. Any good ideas of how to do this in R ? Thanks a lot in advance, Keyan Zhao Computational Biology and Bioinformatics program Univ of Southern California Email: kzhao at usc.edu
specifying values in correlation matrix in nlme
1 message · Keyan Zhao