Hi All I havent seen that lme or lmer allows to specify certain constraints (although I heard one could program ones own covariance structure). Specific constraints, including one on the residual variance can be specified in sas proc mixed. In my model I want to fix the residual variance to the known value of 0. If anyone having an idea about that, I would appreciate letting me know. Thanks Toby
constraining residual variance to zero in lme or lmer
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