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Survival analysis

2 messages · Medic, cpoiw@rt m@iii@g oii chemo@org@uk

#
I can't understand how to do a survival analysis (?Surv ()) when some
event occurred before the start of observation (left censored). If I
understand correctly, there are two methods. I chose a method with: 1)
time from the start of treatment to the event and 2) the indicator of
the event. I did (in my data) the event indicator so:
1 - event, 2 - event before the start of observation, 0 - no event
---
library(survival)
left_censor_data <- read.table("left.csv", header = TRUE, sep = ";")
#sep = ";" it's right!
dput(left_censor_data, file="left_censor_data") #file attached
left_censor_data
   'data.frame':   11 obs. of  2 variables:
   $ timee : int  5 151 33 37 75 14 7 9 1 45 ...
   $ eventt: int  2 0 0 0 0 0 0 2 0 1 ...
   # 1?event, 2 ? event before the start of observation , 0 ? no event

sur <- Surv(time = left_censor_data$timee,  event =
left_censor_data$eventt, type = "left")
  Warning message:
  In Surv(time = left_censor_data$timee, event = left_censor_data$eventt,  :
  Invalid status value, converted to NA

#Why such a message?
#Then everything turns out wrong
#
On 2020-04-17 20:06, Medic wrote:
I have no experience of left censoring beyond the text book.  Is your 
left censored data the SAME event or a different event?
So if I read this data correctly the first observation is left censored. 
  What does the time "5" refer to?  Is that 5 days BEFORE observation the 
event happened?  Or 5 days after another event happened?  My text book 
understanding of left censored data was that your censored points would 
have time 0.
Is the censoring type you want LEFT TRUNCATION rather than LEFT.  If 
they are also right censored I think R Surv calls these Counting.

See: https://folk.ntnu.no/bo/TMA4275/Download/R.tutorialDiez.pdf

Any help?