On Fri, 5 Aug 2005 Julia Reid wrote:
Subject: [R] GAP pointer I am trying to do a simple segregation analysis using the GAP package. I have the documentation for pointer but I desperately need an example so that I can see how to format the datfile and the jobfile. For each individual, I have FamilyId, SubjectId, FatherId, MotherId, and AffectedStatus (0/1). I would like to obtain the likelihood ratio statistic for transmission. I would greatly appreciate any help on this subject. Best to all, Julia Reid
I wouldn't use Pointer myself (there are lots of more recent packages*), but look at the examples in http://cedar.genetics.soton.ac.uk/pub/PROGRAMS/pointer/pointer.tar.Z and the manual, which is in the book: Morton N.E., Rao D.C & Lalouel J-M (1983). Methods in Genetic Epidemiology. Karger PO Box, CH-4009 Basel (Switzerland). ISBN 3-8055-3668-2 which you will find in many academic libraries. David Duffy. * Don't you use Pap or JPap at Myriad?