Hello, I am looking for a package implementing unconditional tests for comparing two binomials (Barnard's test or derivatives). As I am looking for rare genotypes within my groups, my number of subjects in one of the cells of the 2x2 table is often 2-4 resulting in a too conservative result by Fisher's exact test due to the discrete sample space of the test statistic. As I want to use this as a kind of filter for further investigations I am really interested in the additional power for 2x2 tables. Any help or suggestions are really appreciated Thank you very much Thorsten
Thorsten Raff 2nd Medical Department, University Hospital Schleswig-Holstein, Campus Kiel Chemnitzstra?e 33 24116 Kiel GERMANY phone: +49 431 1697-5234 fax: +49 431 1697-1264 email: t.raff<at>med2.uni-kiel.de web: www.uk-s-h.de -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: application/pgp-signature Size: 197 bytes Desc: This is a digitally signed message part. URL: <https://stat.ethz.ch/pipermail/r-help/attachments/20080916/58eac489/attachment.bin>