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cumulative incidence plot vs survival plot

5 messages · array chip, David Winsemius

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On Jun 27, 2011, at 4:31 PM, array chip wrote:

            
First tell us what you think CI is defined as. I suspect it is not the  
same. The KM estimator is cumulative product of (alive-n(dead))/alive  
so is the product of interval survival probabilities. I doubt that  
your definition of CI has a similar denominator.
plot(time, cumsum(dead)) ...?
As above. Specify what you are seeking.

There is a well-defined relationship between S(t) and the cumulative  
hazard. Maybe you should do a little study of those terms in texts  
regarding survival analysis.
Isn't it time you learned to post in plain text?

--
David Winsemius, MD
West Hartford, CT
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Hi David,

Thanks for responding, and plain text ...(didn't realized I was in rich text).

The endpoint is disease recurrence, I was producing a regular KM plot of 
recurrence-free probability. Then someone recommend using cumulative incidence 
is preferred because death was censored in the dataset. I did a little googling, 
I found CI was used often in the context of competing risk. I am totally new to 
competing risk and trying to understand what competing risk means and why CI is 
preferred than KM survival in this context. If you could share your thoughts 
helping me to understand, greatly appreciated.

Searched archive, found people talking about cmprsk package for estimating and 
plotting CI. would that be the same as the code you suggested: plot(time, 
cumsum(dead))

Thanks very much!

John
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On Jun 27, 2011, at 5:04 PM, array chip wrote:

            
I do not think it would. I think this morning's post from Dr Geskus is  
on point here. You should read his 2011 'Biometrics' paper.
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Thank you David. Didn't realized someone posted related topic this morning.

John



----- Original Message ----
From: David Winsemius <dwinsemius at comcast.net>
To: array chip <arrayprofile at yahoo.com>
Cc: r-help at r-project.org
Sent: Mon, June 27, 2011 3:38:36 PM
Subject: Re: [R] cumulative incidence plot vs survival plot
On Jun 27, 2011, at 5:04 PM, array chip wrote:

            
to
is
I do not think it would. I think this morning's post from Dr Geskus is on point 
here. You should read his 2011 'Biometrics' paper.

--David.
is
David Winsemius, MD
West Hartford, CT