"Vallejo, Roger" <Roger.Vallejo at ARS.USDA.GOV> asked:
I would like to know if we can estimate Rg between two binary traits (disease status: alive vs. dead) with the R package. My data: we have 100 full-sib (FS) families, and two random samples (each with n= 200 FS fish) from each FS family were evaluated for disease resistance to two different bacterial diseases, separately. Both traits are not recorded in the same individual; both traits are recorded in different full-sibs from a FS family.
Yes. Check out http://glmm.wikidot.com/ and the R-sig-mixed-models list. MCMCglmm is the package most explicitly for multivariate genetic analysis, but given you have only full sibs, there are a quite a few choices.