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Repeated measures model in R

Manuel Spínola 
Dear list members,

I would like to run a repeated measure model in R and I would like to 
have your advice on how to parameterize the model and which package and 
function should I use..

I have:

Disease rate (number of cases x 1000 people): the response variable
County (it would be the subject)
Year: from 2002 to 2007

My data set is unbalanced (the counties do not have information for all 
the years).
Thank you very much in advance.
Best,

Manuel Sp?nola