meta-analysis

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Dear Kevin,

The standard error of the estimate (SE) is the square root of the sampling variance of the estimate (vi). So, just square 'SE' and use that for 'vi'.

Best,

--
Wolfgang Viechtbauer                        http://www.wvbauer.com/
Department of Methodology and Statistics    Tel: +31 (43) 388-2277
School for Public Health and Primary Care   Office Location:
Maastricht University, P.O. Box 616         Room B2.01 (second floor)
6200 MD Maastricht, The Netherlands         Debyeplein 1 (Randwyck)

----Original Message----
From: r-sig-epi-bounces at stat.math.ethz.ch
[mailto:r-sig-epi-bounces at stat.math.ethz.ch] On Behalf Of Lu, Kevin
Sent: Wednesday, January 27, 2010 09:25 To: r-sig-epi at stat.math.ethz.ch
Subject: [R-sig-Epi] meta-analysis
To someone who could help me:

I am a PhD student, working in the Wageningen University, the
Netherlands. I am now using metafor package to do meta-analysis.

Since there are few studies conducted on my topic, I have to combine
the results from 5 case-control studies and 1 cohort study. But I do
not know how to do it.

I tried this way, first, use the escalc (measure="OR", ai, bi, ci,
gi) to calculate the effect estimate of yi and variance of vi.

I could extract the RR and 95% confidence interval from the cohort
study to get the point estimate of LnRR and SE.

but I can not combine the results from case-control study and the
results from cohort study due to the difference of vi and SE.

For example, if I use rma(yi, vi, data,), I can not get vi (variance)
for the cohort study. I can only get SE for cohort study. How could
solve it?

Thanks for your time.

Best wishes,

Yingchang (Kevin) Lu

PhD student,

Division of Human Nutrition

Wageningen University

Tel: 0031-317-485300

Fax:0031-317-482782

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