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Moran Test for Spatial Autocorrelation - Significance credible or due to misspecification of the model?

Dear Roger,

Thank you very much for your quick reply! Further to what you were asking ad 3.:
[1] 780.2701
Neighbour list object:
Number of regions: 91 
Number of nonzero links: 8168 
Percentage nonzero weights: 98.63543 
Average number of links: 89.75824 
Link number distribution:

87 88 89 90 
 4  3  4 80 
4 least connected regions:
8 10 12 15 with 87 links
80 most connected regions:
1 3 4 5 6 9 11 13 14 16 17 18 19 20 22 23 24 25 27 28 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 51 52 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 with 90 links 

So yes, most points seem connected to eachother. I repeated the tests (approaches A-C) with a two-sided alternative as well as a one-sided less than alternative and got the following results:

# approach A:
# default: Moran's I test under randomisation:
# "greater" p-value = 0.9967
# "two.sided" p-value = 0.00668
# "less" p-value = 0.00334

# approach B:
# binary: Moran's I test under randomisation:
# "greater" p-value = 0.9968
# "two-sided" p-value = 0.0064
# "less" p-value = 0.0032

# approach C:
# inverse: Moran's I test under randomisation:
# "greater" p-value < 2.2e-16
# "two.sided" p-value < 2.2e-16
# "less" p-value = 1

Why might the fact that most of the areas are connected lead to significant negative autocorrelation tough?
When aggregating the duplicated points (of which they are 7 in total) and repeating steps 2.-5. I end up with the following test results:

# approach A:
# default: Moran's I test under randomisation:
# "greater" p-value = 0.5
# "two.sided" p-value = 1
# "less" p-value = 0.5

# approach B:
# binary: Moran's I test under randomisation:
# "greater" p-value = NA
# "two-sided" p-value = 1
# "less" p-value = NA

# approach C:
# inverse: Moran's I test under randomisation:
# "greater" p-value < 2.2e-16
# "two.sided" p-value < 2.2e-16
# "less" p-value = 1

I think it is quite likely that the GPS coordinates I obtained are heavily approximated (the ares are quite large as they represent subdistricts in large states). I shall now try and obtain possibly more accurate coordinates for the 91 areas using the zoom on GoogleEarth...

I appreciate any further comments or suggestions you might have.

Regards,
Julia