[R-meta] combining Means + SD at post, withD + 95% CI
Dear Jorge I think the conv.wald() function in metafor will calculate the variance for you. You do need an up-to-date version of metafor. Michael
On 26/03/2023 21:28, Jorge Teixeira via R-sig-meta-analysis wrote:
Hi all.
I did this to combine studies that provided M+SD, with others for which I
had only MD + 95% CI or p-value.
*Questions: *
i) Is the Vi well calculated below, as the code was given by GPT? n per
group is irrelevant here, right?
ii) Is there a more elegant way to do this?
iii) Can this method backfire in some way or is there something in
particular that I should have in mind?
Thanks! Code below:
library(metafor)
#
dat <- structure(list(study = c("AA", "BB", "CC",
"EE", "DDD"), en = c(9, 41, 29, 8, 13
), em = c(32, 27.5, 28.7, 22.8, 30.5), esd
= c(1.9, 3.8, 5.2,
3.8, 4.9), cn = c(8, 26, 28, 10, 14), cm = c(30.1, 24.9, 26.9,
24.7, 30.2), csd = c(2.4,
3.6, 3, 4.3, 5.1)), row.names = c(NA,
-5L), class = c("tbl_df", "tbl",
"data.frame"))
#
dat <- escalc(measure="MD", m1i=em, sd1i=esd, n1i=en, m2i=cm, sd2i=csd,
n2i=cn, data=dat)
# Now lets had study "XING", which has a MD of 8 (95%CI: 4, 12), n=60;
p=0.001
sampling variance = (CI / 1.96) ^ 2 / (2 * sample size)
(8 / 1.96) ^ 2 / (2 * 6) = 1.388
# Create a new row for study XING
new_row <- data.frame(study = "XING", en = NA, em = NA, esd = NA, cn = NA,
cm = NA, csd = NA, yi = 8, vi = 1.388)
# Add the new row to dat
dat <- rbind(dat, new_row)
#
res <- rma(yi, vi, data=dat)
res
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