-----Original Message-----
From: R-sig-meta-analysis <r-sig-meta-analysis-bounces at r-project.org> On Behalf
Of zeffiro neurometrika.org via R-sig-meta-analysis
Sent: Tuesday, December 3, 2024 17:27
To: r-sig-meta-analysis at r-project.org
Cc: zeffiro neurometrika.org <zeffiro at neurometrika.org>
Subject: [R-meta] meta-analysis with 2 within-subject variables
I have a question about how to set up the metafor code to perform a meta-
analysis using an experimental design that is fairly common in cross-over
treatment studies.
We have continuous outcome measures (mean and sd) from studies in which each
participant was measured 4 times: 1) in both drug and placebo conditions and 2)
both before and after exposure - in a cross-over design. So,
each study is a 2x2 factorial design with 2 repeated measures.
Although it looks to me as if rma.mv is the appropriate program for this
analysis, I am having difficulty determining the syntax showing how to set
things up to properly handle the within subject correlation and was hoping that
someone could point me to a worked example to use as a guide. I have not found
anything addressing meta-analysis modeling of multiple repeated measures in a
single group.
We are starting out with only 5 studies in the initial meta-analysis.
Thanks in advance for any guidance you can provide.
Regards,
Tom