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[R-meta] Omnibus test of moderators in a model with an interaction term

Dear Gabriele

I would not try to interpret anything about the main effects in the 
presence of an interaction. In effect the interaction is saying that the 
effect of one variable depends on the level of the other.

I would not expect the effects of anything to be strictly additive 
unless they were orthogonal. I suspect that if in your main effects only 
model you look at the variance-covariance matrix of the coefficients 
(which you can get with vcov()) you will find a weak correlation between 
your two main effects (cov2cor() helps to convert to correlations).

Michael
On 04/01/2018 16:46, Gabriele Midolo wrote: