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Message-ID: <3f63b8a6ab8f466bb3223c05407333c4@UM-MAIL3214.unimaas.nl>
Date: 2019-10-10T11:42:46Z
From: Wolfgang Viechtbauer
Subject: [R-meta] Meta-regression of proportions using rma.glmm
In-Reply-To: <CABgeOtOMHdPQ9s-20VG+1B34mecB4n8TdKYQwS2SdUq33fpDrw@mail.gmail.com>

Dear Daniel,

No, studies with 0 events are not removed. To illustrate:

library(metafor)

xi <- c(0,1,0,0,1,2)
ni <- rep(10,6)

res <- rma.glmm(measure="PLO", xi=xi, ni=ni)
res
predict(res, transf=exp)

res <- rma.glmm(measure="PLO", xi=xi, ni=ni, subset=xi>0)
res
predict(res, transf=exp)

As you can see, in the second model, the estimate of the odds is much higher, since there I have explicitly thrown out the studies with 0 events.

Best,
Wolfgang

-----Original Message-----
From: Daniel M?nsted Shabanzadeh [mailto:dmshaban at gmail.com] 
Sent: Thursday, 10 October, 2019 10:11
To: Viechtbauer, Wolfgang (SP); r-sig-meta-analysis at r-project.org
Subject: Meta-regression of proportions using rma.glmm

Hey

I am performing af meta-regression of post-operative complications in single-arm studies. I am using the rma.glmm function on logit transformed data (measure ="PLO").?Many of the studies have 0 events - are these studie's proportions?removed from the model? In that?case, how can i include them?

Regards,
Daniel??

Daniel M?nsted Shabanzadeh
MD, PhD
Department of Gastroenterology, Surgical Unit
Hvidovre Hospital
Mobile?+45 2546 5251?