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Message-ID: <5378b715-5d14-3239-8fee-318611b07e30@dewey.myzen.co.uk>
Date: 2020-12-05T16:16:24Z
From: Michael Dewey
Subject: [R-meta] Meta-analysis with only p.values and N?
In-Reply-To: <8c08aaf9-f484-4c5d-a063-779b9d309cce@email.android.com>

Those methods have their uses but if Raquel wants a forest plot I do not 
think they generate the required effect size with its confidence interval.

Michael

On 05/12/2020 14:19, t.saueressig at gmx.de wrote:
> Dear Raquel,
> 
> in Boerenstein et al. 2009 (Handbook) there is a description of a method 
> to combine p values for a pooled p value. Maybe that would be a solution?
> 
> Regards,
> 
> Tobias Saueressig
> 
> Am 05.12.2020 12:21 schrieb Michael Dewey <lists at dewey.myzen.co.uk>:
> 
>     Dear Raquel
> 
>     If you have the means or the difference in means as well then you can
>     back-calculate what you need but if not I am afraid I can see no way
>     forward although other smarter list readers may be able to help.
> 
>     Michael
> 
>     On 04/12/2020 18:45, Raquel Cumeras Olmeda wrote:
>      > Dear all,
>      >
>      > We are trying to do a meta-analysis of metabolomics data.
>      > In metabolomics, we study the changes of the concentrations of
>     compounds in biofluids.
>      >
>      > So, for the data I am trying to analyze I have the p.value of the
>     relevant compounds and the N of the patients and controls.
>      >
>      > We tried to do a forest plot, but we don't know how to do it with
>     only the p.value and the N.
>      >
>      > Any help would be more than welcome!
>      >
>      > Raquel Cumeras
>      >
>      >
>     -----------------------------------------------------------------------------------------------
> 
>      > Raquel Cumeras, Ph.D.
>      > Marie Curie Postdoctoral Research Fellow
>      > - Institut d'Investigaci? Sanit?ria Pere Virgili (IISPV, ES).
>     Metabolomics Platform<http://metabolomicsplatform.com/>.
>      > - University of California Davis (UC Davis, USA). Fiehn lab.
>      > - Affiliated to Universitat Rovira i Virgili (URV, ES) and
>     CIBERDEM (ISCIII, ES).
>      >
>      > website: https://raquelcumeras.wordpress.com/
>      > e_mail: raquel.cumeras at iispv.cat<mailto:raquel.cumeras at iispv.cat>
>     // rcumeras at ucdavis.edu<mailto:rcumeras at ucdavis.edu> //
>     raquel.cumeras at urv.cat<mailto:raquel.cumeras at urv.cat>
>      > ORCiD: 0000-0003-4663-4247
>      > Pronouns: she/her
>      >
>     -----------------------------------------------------------------------------------------------
> 
>      >
>      >
>      > [[alternative HTML version deleted]]
>      >
>      >
>      >
>      >
>      > _______________________________________________
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>      >
> 
>     -- 
>     Michael
>     http://www.dewey.myzen.co.uk/home.html
> 
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-- 
Michael
http://www.dewey.myzen.co.uk/home.html