[R-meta] Meta-analysis of mean differences
Hi all. How should I do a meta-analysis of mean differences having the initial and final values ??with their standard deviations for each group. With the metacont function I can only put mean 1, standard deviation 1 mean 1 and standard deviation 2 with their respective n. I think I should use a meta analysis of score changes but I don't know how to do it in R. regards Lorenzo Mart?n Lobo MTSAC, FACC, FESC Especialista Jerarquizado en Cardiolog?a Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo. Jefe de Cardiolog?a Hospital Militar Campo de Mayo Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo Miembro Titular de la Sociedad Argentina de Cardiolog?a Fellow American College of Cardiology Fellow European Society of Cardiology Ex Miembro del Area de Investigaci?n de la SAC Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC Ex Director del Consejo de Epidemiolog?a y Prevenci?n Cardiovascular de la SAC Miembro Asesor del Consejo de Epidemiolog?a y Prevenci?n Cardiovascular de la SAC Experto en Lipidos de la Sociedad Argentina de Lipidos. Miembro de la Sociedad Argentina de Lipidos. Instructor de ACLS de la American Heart Association
De: Dr. Gerta R?cker <ruecker at imbi.uni-freiburg.de>
Enviado: viernes, 17 de septiembre de 2021 09:44 Para: Martin Lobo <mlobo4370 at hotmail.com>; r-sig-meta-analysis at r-project.org <r-sig-meta-analysis at r-project.org> Asunto: Re: [R-meta] meta-analysis of mean differences with only the difference and its SD Dear Martin, Again: Where is the problem? If you have the differences and their standard deviation from all studies, you can simply pool them in a meta-analysis of change scores. Or is the problem that you have differences for some studies and post values for others? Probably this helps: https://training.cochrane.org/handbook/current/chapter-10#section-10-5-2<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Ftraining.cochrane.org%2Fhandbook%2Fcurrent%2Fchapter-10%23section-10-5-2&data=04%7C01%7C%7C05240848802d49dd05b508d979d8d6fb%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637674794702961214%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=k2pBsOMbHyJKJQbbR%2F%2BcdDPIuEMcYeIpbILpnM2FOKU%3D&reserved=0> Best, Gerta Am 17.09.2021 um 14:35 schrieb Martin Lobo: Hi Gerta. Thanks. My question is how to perform the meta analysis having only the difference. The ones that I have done put the pre and post values, in this I already have the difference. it would be a single branch. Than`s again Lorenzo Mart?n Lobo MTSAC, FACC, FESC ________________________________ From: Dr. Gerta R?cker <ruecker at imbi.uni-freiburg.de><mailto:ruecker at imbi.uni-freiburg.de> Sent: Thursday, September 16, 2021 2:33:48 PM To: Martin Lobo <mlobo4370 at hotmail.com><mailto:mlobo4370 at hotmail.com>; r-sig-meta-analysis at r-project.org<mailto:r-sig-meta-analysis at r-project.org> <r-sig-meta-analysis at r-project.org><mailto:r-sig-meta-analysis at r-project.org> Subject: Re: [R-meta] meta-analysis of mean differences with only the difference and its SD Dear Martin, I don't understand your problem. - You write you want to do meta-analysis of differences of means. Do you mean pre-post differences? It is not clear. - You further write you have the difference with its standard deviations, not the initial (pre) or the final (post) values. So, why do you ask how to calculate the difference if you already have it? Please clarify. Best, Gerta Am 15.09.2021 um 15:23 schrieb Martin Lobo: Hello everyone, I need to do a meta-analysis of differences of means. I have the difference with its standard deviations, I do not have the initial or final values. What method should I use in this case to have only the value of the difference? The generic method of variance? Thank you Lorenzo Mart?n Lobo MTSAC, FACC, FESC Especialista Jerarquizado en Cardiolog?a Jefe de Dpto Enf. Cardiovasculares y Cardiometabolismo Hospital Militar Campo de Mayo. Jefe de Cardiolog?a Hospital Militar Campo de Mayo Ex Jefe de Unidad Coronaria Hospital Militar Campo de Mayo Miembro Titular de la Sociedad Argentina de Cardiolog?a Fellow American College of Cardiology Fellow European Society of Cardiology Ex Miembro del Area de Investigaci?n de la SAC Ex Director del Consejo de Aterosclerosis y Trombosis de la SAC Miembro Asesor del Consejo de Aterosclerosis y Trombosis de la SAC Ex Director del Consejo de Epidemiolog?a y Prevenci?n Cardiovascular de la SAC Miembro Asesor del Consejo de Epidemiolog?a y Prevenci?n Cardiovascular de la SAC Experto en Lipidos de la Sociedad Argentina de Lipidos. Miembro de la Sociedad Argentina de Lipidos. Instructor de ACLS de la American Heart Association _______________________________________________ R-sig-meta-analysis mailing list R-sig-meta-analysis at r-project.org<mailto:R-sig-meta-analysis at r-project.org> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fstat.ethz.ch%2Fmailman%2Flistinfo%2Fr-sig-meta-analysis&data=04%7C01%7C%7C05240848802d49dd05b508d979d8d6fb%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637674794702961214%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=vQI7G5g4TYHBiZAmhH2XvWtQWZ%2FLajNHNTnsyvc7%2B70%3D&reserved=0> -- Dr. rer. nat. Gerta R?cker, Dipl.-Math. Guest Scientist Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg Zinkmattenstr. 6a, D-79108 Freiburg, Germany Mail: ruecker at imbi.uni-freiburg.de<mailto:ruecker at imbi.uni-freiburg.de> Homepage: https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.uniklinik-freiburg.de%2Fimbi-en%2Femployees.html%3Fimbiuser%3Druecker&data=04%7C01%7C%7C05240848802d49dd05b508d979d8d6fb%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637674794702971212%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=sVXwDzAAOmll0TzlhLfXpQa0SFPzP%2FRsHdb8NROL354%3D&reserved=0> -- Dr. rer. nat. Gerta R?cker, Dipl.-Math. Guest Scientist Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg Zinkmattenstr. 6a, D-79108 Freiburg, Germany Mail: ruecker at imbi.uni-freiburg.de<mailto:ruecker at imbi.uni-freiburg.de> Homepage: https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fwww.uniklinik-freiburg.de%2Fimbi-en%2Femployees.html%3Fimbiuser%3Druecker&data=04%7C01%7C%7C05240848802d49dd05b508d979d8d6fb%7C84df9e7fe9f640afb435aaaaaaaaaaaa%7C1%7C0%7C637674794702981208%7CUnknown%7CTWFpbGZsb3d8eyJWIjoiMC4wLjAwMDAiLCJQIjoiV2luMzIiLCJBTiI6Ik1haWwiLCJXVCI6Mn0%3D%7C1000&sdata=VoDSfCkqy5O5zp4tT%2Bi%2BAmSnFb1aHGdxJbDkY%2F5yeHY%3D&reserved=0>