[R-meta] Subgroup comparison for non-linear meta-regression
Dear all, I did a ?non-linear? meta-regression for prevalence (proportion) on time variable (year) using a power function. The studies consist of information for male and female participants. I would like to assess whether the non-linear fit was similar for male and female. In other words, I would like to make a comparison for male and female. I think it is more appropriate to do a meta-regression including gender*time interaction, however, number of the studies is small. My questions are: 1) Is it acceptable just to compare the subgroups (as stated below) without using interaction term. If it is acceptable; 2) Does metafor package has a command like ?byvar? that makes a statistical comparison of two subgroups possible? If not, 2) Is it appropriate to calculate z=(p1-p1)/sqrt(se1^2 +se2^2) and then p for a ?non-linear? relationship? Kind regards Mustafa Kilickap