---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are 3-4 new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there any other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already performed meta-analysis. Can I add the meta analysis studies HRs and new studies to make another meta-analysis ? Please guide me which review could be the best in this situation. best regards
[R-meta] Fwd: Question on Umbrella review and other types
12 messages · Dr. Gerta Rücker, Michael Dewey, Im
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies included in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are 3-4 new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there any other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already performed meta-analysis. Can I add the meta analysis studies HRs and new studies to make another meta-analysis ? Please guide me which review could be the best in this situation. best regards _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael
On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies included in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are 3-4 new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there any other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already performed meta-analysis. Can I add the meta analysis studies HRs and new studies to make another meta-analysis ? Please guide me which review could be the best in this situation. best regards [[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
Michael
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the same review. Since this is now better done using network meta-analysis, they now use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis <r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael
On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies included in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are 3-4 new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there any other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already performed meta-analysis. Can I add the meta analysis studies HRs and new studies to make another meta-analysis ? Please guide me which review could be the best in this situation. best regards [[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
Michael
Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old age have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of studies published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better to conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with a gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis <
r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the same review. Since this is now better done using network meta-analysis, they now use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all
studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies included in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are
3-4
new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there
any
other type of review that could be performed ? I want to include the
previous systematic/meta reviews. I also plan to repeat already performed
meta-analysis. Can I add the meta analysis studies HRs and new studies to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
-- Michael
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
Hi Imran, I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results. You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with "year published" as a covariate. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 20:46 An: R Special Interest Group for Meta-Analysis <r-sig-meta-analysis at r-project.org> Cc: Im <aligners79 at gmail.com> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old age have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of studies published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better to conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with a gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis <
r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the same review. Since this is now better done using network meta-analysis, they now use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all
studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies included in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are
3-4
new studies published after or almost at same time of these two reviews. My question is can I conduct the Umbrella review ? If not then is there
any
other type of review that could be performed ? I want to include the
previous systematic/meta reviews. I also plan to repeat already performed
meta-analysis. Can I add the meta analysis studies HRs and new studies to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
-- Michael
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
Hello Dr Gerta! Thanks for your valuable suggestion. Could You please share with me the R codes, package for metaregression, and a brief method if I need to do this analysis ? I would be much grateful. best regards, Imran On Mon, Apr 22, 2024 at 10:43?PM Dr. Gerta R?cker <
gerta.ruecker at uniklinik-freiburg.de> wrote:
Hi Imran, I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results. You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with "year published" as a covariate. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 20:46 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Im <aligners79 at gmail.com> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old age have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of studies published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better to conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with a gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis < r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the same review. Since this is now better done using network meta-analysis, they
now
use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all
studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies
included
in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are
3-4
new studies published after or almost at same time of these two
reviews.
My question is can I conduct the Umbrella review ? If not then is there
any
other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already
performed
meta-analysis. Can I add the meta analysis studies HRs and new studies
to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
-- Michael
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
[[alternative HTML version deleted]]
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Dear Imran, On https://cran.r-project.org/web/packages/meta/index.html (Documentation) you find links to the help file of the R package meta (meta.pdf) and to a very basic tutorial. The help file contains help for all functions, particularly metareg.meta() or briefly metareg() that is a wrapper function of rma.uni() from the R package metafor. You find there an example of a metaregression. Or type help(package = "meta") to get the online help. Of course, you can also use the metafor package directly. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Dienstag, 23. April 2024 09:44 An: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Cc: Im <aligners79 at gmail.com>; R Special Interest Group for Meta-Analysis <r-sig-meta-analysis at r-project.org> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Hello Dr Gerta! Thanks for your valuable suggestion. Could You please share with me the R codes, package for metaregression, and a brief method if I need to do this analysis ? I would be much grateful. best regards, Imran On Mon, Apr 22, 2024 at 10:43?PM Dr. Gerta R?cker <
gerta.ruecker at uniklinik-freiburg.de> wrote:
Hi Imran, I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results. You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with "year published" as a covariate. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 20:46 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Im <aligners79 at gmail.com> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old age have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of studies published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better to conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with a gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis < r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the same review. Since this is now better done using network meta-analysis, they
now
use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by umbrella is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all
studies adhere to some common well-defined inclusion criteria, then why not conducting a meta-analysis including the union of all studies
included
in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies are
3-4
new studies published after or almost at same time of these two
reviews.
My question is can I conduct the Umbrella review ? If not then is there
any
other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already
performed
meta-analysis. Can I add the meta analysis studies HRs and new studies
to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
-- Michael
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
[[alternative HTML version deleted]]
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_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
If you are going to update the review I suggest best practice is to redo the search as otherwise you are importain any biases introduced by the authors of the previous reviews. Michael
On 22/04/2024 19:45, Im wrote:
Dear All!
Many thanks indeed for your much valuable replies.
My research is based on "Prognosis in relation to age in a carcinoma".
The study results are "young age patients have better prognosis", "old
age have?worst prognosis", "age has not affect on prognostication" etc....
Is it possible to be selective in the studies in terms of time
of?studies published etc., so that there can be some change in the
analysis than?previous ones ?
With such a trivial number (only two) of previous SRMA, it seems better
to conduct a new SRMA instead. But I am bit concerned whether?it is Ok
to?conduct a new SRMA when the?previously?SRMA have?been published with
a gap of?just couple of?years (2020 and 2021)?
So, if there is no problem in conducting a new SRMA, then I would?be add
the studies and proceed with the routine "meta" package in R studios for
forest plots and funnel plots ?
best regards,
Imran
On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>> wrote:
Yes,I have noted that the word "umbrella" has experienced a change
of meaning over the last years. In former times (that is, before
network meta-analysis became popular) it meant to conduct a number
of pairwise meta-analyses for different treatments for the same
condition in the same review. Since this is now better done using
network meta-analysis, they now use the term for something
different, namely overview of overviews, and this is what the
original poster meant.
As I understand, in the described situation, a re-analysis is
planned, thus I am not sure whether a special R package is needed.
Best,
Gerta
UNIVERSIT?TSKLINIKUM FREIBURG
Institute for Medical Biometry and Statistics
Dr. Gerta R?cker
Guest Scientist
Stefan-Meier-Stra?e 26 ? 79104 Freiburg
gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>
https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker <https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker>
-----Urspr?ngliche Nachricht-----
Von: Michael Dewey <lists at dewey.myzen.co.uk
<mailto:lists at dewey.myzen.co.uk>>
Gesendet: Montag, 22. April 2024 17:23
An: R Special Interest Group for Meta-Analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>>
Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types
There is a package https://cran.r-project.org/package=metaumbrella
<https://cran.r-project.org/package=metaumbrella> on
CRAN which performs umbrella reviews. Whether what they mean by
umbrella
is what you mean is open to question.
Michael
On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
> Hi (whoever you are),
>
> If you want to repeat the old meta-analysis anyway, assuming that
all studies adhere to some common well-defined inclusion criteria,
then why not conducting a meta-analysis including the union of all
studies included in the two older reviews and the new studies? This
would simply be an updated review, not necessarily an umbrella review.
>
> Best,
> Gerta
>
>
> UNIVERSIT?TSKLINIKUM FREIBURG
> Institute for Medical Biometry and Statistics
>
> Dr. Gerta R?cker
> Guest Scientist
>
> Stefan-Meier-Stra?e 26 ? 79104 Freiburg
> gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>
>
>
https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker <https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker>
>
> -----Urspr?ngliche Nachricht-----
> Von: Im via R-sig-meta-analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
> Gesendet: Montag, 22. April 2024 15:47
> An: r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>
> Cc: Im <aligners79 at gmail.com <mailto:aligners79 at gmail.com>>
> Betreff: [R-meta] Fwd: Question on Umbrella review and other types
>
> ---------- Forwarded message ---------
> From: Im <aligners79 at gmail.com <mailto:aligners79 at gmail.com>>
> Date: Mon, Apr 22, 2024 at 12:56?PM
> Subject: Question on Umbrella review and other types
> To: <r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
>
>
>
> Hello!
>? ?I am planning to do an Umbrella review.
>
> The number of systematic/meta analysis are two. Rest of the
studies are 3-4
> new studies published after or almost at same time of these two
reviews.
>
> My question is can I conduct the Umbrella review ? If not then is
there any
> other type of review that could be performed ?? I want to include the
> previous systematic/meta reviews. I also plan to repeat already
performed
> meta-analysis. Can I add the meta analysis studies HRs and new
studies to
> make another meta-analysis ?
>
> Please guide me which review could be the best in this situation.
> best regards
>
>? ? ? ?[[alternative HTML version deleted]]
>
> _______________________________________________
> R-sig-meta-analysis mailing list @
R-sig-meta-analysis at r-project.org
<mailto:R-sig-meta-analysis at r-project.org>
> To manage your subscription to this mailing list, go to:
> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
> _______________________________________________
> R-sig-meta-analysis mailing list @
R-sig-meta-analysis at r-project.org
<mailto:R-sig-meta-analysis at r-project.org>
> To manage your subscription to this mailing list, go to:
> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
>
>
--
Michael
_______________________________________________
R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org
<mailto:R-sig-meta-analysis at r-project.org>
To manage your subscription to this mailing list, go to:
https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
<https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis>
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Michael
Dear Dr Gerta! Thanks a lot for your much valuable suggestions, I will proceed accordingly. best regards, Imran On Tue, Apr 23, 2024 at 12:53?PM Dr. Gerta R?cker <
gerta.ruecker at uniklinik-freiburg.de> wrote:
Dear Imran, On https://cran.r-project.org/web/packages/meta/index.html (Documentation) you find links to the help file of the R package meta (meta.pdf) and to a very basic tutorial. The help file contains help for all functions, particularly metareg.meta() or briefly metareg() that is a wrapper function of rma.uni() from the R package metafor. You find there an example of a metaregression. Or type help(package = "meta") to get the online help. Of course, you can also use the metafor package directly. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Dienstag, 23. April 2024 09:44 An: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Cc: Im <aligners79 at gmail.com>; R Special Interest Group for Meta-Analysis <r-sig-meta-analysis at r-project.org> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Hello Dr Gerta! Thanks for your valuable suggestion. Could You please share with me the R codes, package for metaregression, and a brief method if I need to do this analysis ? I would be much grateful. best regards, Imran On Mon, Apr 22, 2024 at 10:43?PM Dr. Gerta R?cker < gerta.ruecker at uniklinik-freiburg.de> wrote:
Hi Imran, I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results. You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with
"year
published" as a covariate. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 20:46 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Im <aligners79 at gmail.com> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old
age
have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of studies published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better
to
conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with a gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis
<
r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the
same
review. Since this is now better done using network meta-analysis, they
now
use the term for something different, namely overview of overviews, and this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by
umbrella
is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that all
studies adhere to some common well-defined inclusion criteria, then
why
not conducting a meta-analysis including the union of all studies
included
in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies
are
3-4
new studies published after or almost at same time of these two
reviews.
My question is can I conduct the Umbrella review ? If not then is
there
any
other type of review that could be performed ? I want to include the previous systematic/meta reviews. I also plan to repeat already
performed
meta-analysis. Can I add the meta analysis studies HRs and new
studies
to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis _______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
-- Michael
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
[[alternative HTML version deleted]]
_______________________________________________ R-sig-meta-analysis mailing list @ R-sig-meta-analysis at r-project.org To manage your subscription to this mailing list, go to: https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
Dear Dr Michael! Thanks a lot for your much valuable suggestions, I will proceed accordingly. best regards, Imran On Tue, Apr 23, 2024 at 2:04?PM Michael Dewey <lists at dewey.myzen.co.uk> wrote:
If you are going to update the review I suggest best practice is to redo the search as otherwise you are importain any biases introduced by the authors of the previous reviews. Michael On 22/04/2024 19:45, Im wrote:
Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old age have worst prognosis", "age has not affect on prognostication"
etc....
Is it possible to be selective in the studies in terms of time
of studies published etc., so that there can be some change in the
analysis than previous ones ?
With such a trivial number (only two) of previous SRMA, it seems better
to conduct a new SRMA instead. But I am bit concerned whether it is Ok
to conduct a new SRMA when the previously SRMA have been published with
a gap of just couple of years (2020 and 2021)?
So, if there is no problem in conducting a new SRMA, then I would be add
the studies and proceed with the routine "meta" package in R studios for
forest plots and funnel plots ?
best regards,
Imran
On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via R-sig-meta-analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>> wrote:
Yes,I have noted that the word "umbrella" has experienced a change
of meaning over the last years. In former times (that is, before
network meta-analysis became popular) it meant to conduct a number
of pairwise meta-analyses for different treatments for the same
condition in the same review. Since this is now better done using
network meta-analysis, they now use the term for something
different, namely overview of overviews, and this is what the
original poster meant.
As I understand, in the described situation, a re-analysis is
planned, thus I am not sure whether a special R package is needed.
Best,
Gerta
UNIVERSIT?TSKLINIKUM FREIBURG
Institute for Medical Biometry and Statistics
Dr. Gerta R?cker
Guest Scientist
Stefan-Meier-Stra?e 26 ? 79104 Freiburg
gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>
https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker <https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker
-----Urspr?ngliche Nachricht-----
Von: Michael Dewey <lists at dewey.myzen.co.uk
<mailto:lists at dewey.myzen.co.uk>>
Gesendet: Montag, 22. April 2024 17:23
An: R Special Interest Group for Meta-Analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>>
Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other
types
There is a package https://cran.r-project.org/package=metaumbrella
<https://cran.r-project.org/package=metaumbrella> on
CRAN which performs umbrella reviews. Whether what they mean by
umbrella
is what you mean is open to question.
Michael
On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
> Hi (whoever you are),
>
> If you want to repeat the old meta-analysis anyway, assuming that
all studies adhere to some common well-defined inclusion criteria,
then why not conducting a meta-analysis including the union of all
studies included in the two older reviews and the new studies? This
would simply be an updated review, not necessarily an umbrella
review.
>
> Best,
> Gerta
>
>
> UNIVERSIT?TSKLINIKUM FREIBURG
> Institute for Medical Biometry and Statistics
>
> Dr. Gerta R?cker
> Guest Scientist
>
> Stefan-Meier-Stra?e 26 ? 79104 Freiburg
> gerta.ruecker at uniklinik-freiburg.de
<mailto:gerta.ruecker at uniklinik-freiburg.de>
>
>
https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker <https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker
>
> -----Urspr?ngliche Nachricht-----
> Von: Im via R-sig-meta-analysis
<r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
> Gesendet: Montag, 22. April 2024 15:47
> An: r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>
> Cc: Im <aligners79 at gmail.com <mailto:aligners79 at gmail.com>>
> Betreff: [R-meta] Fwd: Question on Umbrella review and other types
>
> ---------- Forwarded message ---------
> From: Im <aligners79 at gmail.com <mailto:aligners79 at gmail.com>>
> Date: Mon, Apr 22, 2024 at 12:56?PM
> Subject: Question on Umbrella review and other types
> To: <r-sig-meta-analysis at r-project.org
<mailto:r-sig-meta-analysis at r-project.org>>
>
>
>
> Hello!
> I am planning to do an Umbrella review.
>
> The number of systematic/meta analysis are two. Rest of the
studies are 3-4
> new studies published after or almost at same time of these two
reviews.
>
> My question is can I conduct the Umbrella review ? If not then is
there any
> other type of review that could be performed ? I want to include
the
> previous systematic/meta reviews. I also plan to repeat already
performed
> meta-analysis. Can I add the meta analysis studies HRs and new
studies to
> make another meta-analysis ?
>
> Please guide me which review could be the best in this situation.
> best regards
>
> [[alternative HTML version deleted]]
>
> _______________________________________________
> R-sig-meta-analysis mailing list @
R-sig-meta-analysis at r-project.org
<mailto:R-sig-meta-analysis at r-project.org>
> To manage your subscription to this mailing list, go to:
> https://stat.ethz.ch/mailman/listinfo/r-sig-meta-analysis
> _______________________________________________
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Dear Dr Gerta and Dr Michael! Sorry to bother You again. There is one concern. The two systematic reviews have come to almost same main conclusion that young patients have higher chances of recurrence, and few other findings. However, one conclusion is quite definite and second is not much definite. Do You think it will be Ok to do the SRMA with inclusion of additional studies in previous studies ? And also I would need to register the study in PROSPERO as usual. My boss was thinking earlier of having a review study on previously published studies, how that sounds ? best regards, Imran
On Wed, Apr 24, 2024 at 10:55?AM Im <aligners79 at gmail.com> wrote:
Dear Dr Gerta! Thanks a lot for your much valuable suggestions, I will proceed accordingly. best regards, Imran On Tue, Apr 23, 2024 at 12:53?PM Dr. Gerta R?cker < gerta.ruecker at uniklinik-freiburg.de> wrote:
Dear Imran, On https://cran.r-project.org/web/packages/meta/index.html (Documentation) you find links to the help file of the R package meta (meta.pdf) and to a very basic tutorial. The help file contains help for all functions, particularly metareg.meta() or briefly metareg() that is a wrapper function of rma.uni() from the R package metafor. You find there an example of a metaregression. Or type help(package = "meta") to get the online help. Of course, you can also use the metafor package directly. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de https://www.uniklinik-freiburg.de/imbi-en/employees.html?imbiuser=ruecker -----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Dienstag, 23. April 2024 09:44 An: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Cc: Im <aligners79 at gmail.com>; R Special Interest Group for Meta-Analysis <r-sig-meta-analysis at r-project.org> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Hello Dr Gerta! Thanks for your valuable suggestion. Could You please share with me the R codes, package for metaregression, and a brief method if I need to do this analysis ? I would be much grateful. best regards, Imran On Mon, Apr 22, 2024 at 10:43?PM Dr. Gerta R?cker < gerta.ruecker at uniklinik-freiburg.de> wrote:
Hi Imran, I think the publication of new studies justifies an updated review, particularly if the existing reviews have inconsistent or inconclusive results. You should, however, avoid to be selective with the studies, let alone selective based on the results! This would be publication bias. What you can do if you suppose there is a time effect is a metaregression with
"year
published" as a covariate. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 20:46 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Im <aligners79 at gmail.com> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types Dear All! Many thanks indeed for your much valuable replies. My research is based on "Prognosis in relation to age in a carcinoma". The study results are "young age patients have better prognosis", "old
age
have worst prognosis", "age has not affect on prognostication" etc.... Is it possible to be selective in the studies in terms of time of
studies
published etc., so that there can be some change in the analysis than previous ones ? With such a trivial number (only two) of previous SRMA, it seems better
to
conduct a new SRMA instead. But I am bit concerned whether it is Ok to conduct a new SRMA when the previously SRMA have been published with
a
gap of just couple of years (2020 and 2021)? So, if there is no problem in conducting a new SRMA, then I would be add the studies and proceed with the routine "meta" package in R studios for forest plots and funnel plots ? best regards, Imran On Mon, Apr 22, 2024 at 6:35?PM Dr. Gerta R?cker via
R-sig-meta-analysis <
r-sig-meta-analysis at r-project.org> wrote:
Yes,I have noted that the word "umbrella" has experienced a change of meaning over the last years. In former times (that is, before network meta-analysis became popular) it meant to conduct a number of pairwise meta-analyses for different treatments for the same condition in the
same
review. Since this is now better done using network meta-analysis,
they
now
use the term for something different, namely overview of overviews,
and
this is what the original poster meant. As I understand, in the described situation, a re-analysis is planned, thus I am not sure whether a special R package is needed. Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Michael Dewey <lists at dewey.myzen.co.uk> Gesendet: Montag, 22. April 2024 17:23 An: R Special Interest Group for Meta-Analysis < r-sig-meta-analysis at r-project.org> Cc: Dr. Gerta R?cker <gerta.ruecker at uniklinik-freiburg.de> Betreff: Re: [R-meta] Fwd: Question on Umbrella review and other types There is a package https://cran.r-project.org/package=metaumbrella on CRAN which performs umbrella reviews. Whether what they mean by
umbrella
is what you mean is open to question. Michael On 22/04/2024 15:44, Dr. Gerta R?cker via R-sig-meta-analysis wrote:
Hi (whoever you are), If you want to repeat the old meta-analysis anyway, assuming that
all
studies adhere to some common well-defined inclusion criteria, then
why
not conducting a meta-analysis including the union of all studies
included
in the two older reviews and the new studies? This would simply be an updated review, not necessarily an umbrella review.
Best, Gerta UNIVERSIT?TSKLINIKUM FREIBURG Institute for Medical Biometry and Statistics Dr. Gerta R?cker Guest Scientist Stefan-Meier-Stra?e 26 ? 79104 Freiburg gerta.ruecker at uniklinik-freiburg.de
-----Urspr?ngliche Nachricht----- Von: Im via R-sig-meta-analysis <r-sig-meta-analysis at r-project.org> Gesendet: Montag, 22. April 2024 15:47 An: r-sig-meta-analysis at r-project.org Cc: Im <aligners79 at gmail.com> Betreff: [R-meta] Fwd: Question on Umbrella review and other types ---------- Forwarded message --------- From: Im <aligners79 at gmail.com> Date: Mon, Apr 22, 2024 at 12:56?PM Subject: Question on Umbrella review and other types To: <r-sig-meta-analysis at r-project.org> Hello! I am planning to do an Umbrella review. The number of systematic/meta analysis are two. Rest of the studies
are
3-4
new studies published after or almost at same time of these two
reviews.
My question is can I conduct the Umbrella review ? If not then is
there
any
other type of review that could be performed ? I want to include
the
previous systematic/meta reviews. I also plan to repeat already
performed
meta-analysis. Can I add the meta analysis studies HRs and new
studies
to
make another meta-analysis ?
Please guide me which review could be the best in this situation.
best regards
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