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Minimum detectable effect size in linear mixed model

Dear Han,

I agree with your interpretation of a sensitivity analysis that shows a correlation of .6 would be needed to have the desired power in a situation where .2 would be typical. To achieve desired sensitivity, we could increase sample size, or increase alpha (i.e., go to .10 instead of .05), or we could reduce our desired power (maybe be satisfied with .80 or less instead of .90 or .95), or we could try to increase the effect size, perhaps by using better measures or a more intense treatment. 

If we wish to determine an appropriate sample size, we specify alpha, power, and the effect size. Setting the effect size is tricky because we don't know the actual effect. A logical approach is to set the effect size at the smallest value that is considered to be important. If the effect size is larger, we will have even more power. If the effect size is smaller, we don't care much if the result is not statistically significant. 

I used the acronym BEAN to help people remember the four features that are involved with power analysis. 

B = beta error, where power = (1 ? Beta error)
E = effect size
A = alpha error rate
N = sample size

If you know any three, you can compute the fourth. 

Best 
Sacha

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