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optimizers for mixed models

Ross Boylan <ross at ...> writes:
Which package?

 A couple more points:

 * I don't know offhand which optimizing tools in R (1) allow for
box constraints and (2) can take both a user-specified gradient
and a user-specified hessian (there are several that take user-specified
gradients); I think there may be some in optreplace/optimx, but I'm not
sure.

 * according to Dave Fournier, AD Model Builder actually can do GH
quadrature with multiple terms per random effect (the documentation
is wrong/out of date), so you might look into that ...  (as I recall
this is a single RE with multiple terms, not crossed RE -- right?)

  Ben