Convergence in binomial MCMCglmm
On Wed, 8 Jun 2011, Jarrod Hadfield wrote:
I'm not sure that censoring can be adequately handled when treating survival as a series of 0 binary outcomes ending in a 1, but I would be interested if anyone knows how it could be dealt with?
I would have thought about this problem as a "conventional" mixed model for survival data with time varying covariates: so as a "counting process" model. The coxme package can fit this - I have only used it for ordinary right censored type data, so I can't give specific advice. To do this kind of thing in an MCMC framework, I think one usually does it as a piecewise exponential eg Scurrah K et al Variance components analysis for pedigree-based censored survival data using generalized linear mixed models (GLMMs) and Gibbs sampling in BUGS. Genetic Epidemiology Volume 19, Issue 2, pages 127-148, September 2000. You can ask Katrina S about this. Cheers, David Duffy.
| David Duffy (MBBS PhD) ,-_|\ | email: davidD at qimr.edu.au ph: INT+61+7+3362-0217 fax: -0101 / * | Epidemiology Unit, Queensland Institute of Medical Research \_,-._/ | 300 Herston Rd, Brisbane, Queensland 4029, Australia GPG 4D0B994A v