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How to analyse data with two replicates per group

Dear Simon,

IMHO you should use individual as a random effect. If a systematic
difference between both eyes are relevant / plausible, then add a variable
coding for left or right to the fixed effect. Otherwise, don't include it
in the model.

Create a subset of the data which has no missing values in all variables
used in your full model. Fit all your models on this subset. Then you can
compare AIC.

Best regards,

ir. Thierry Onkelinx
Statisticus / Statistician

Vlaamse Overheid / Government of Flanders
INSTITUUT VOOR NATUUR- EN BOSONDERZOEK / RESEARCH INSTITUTE FOR NATURE AND
FOREST
Team Biometrie & Kwaliteitszorg / Team Biometrics & Quality Assurance
thierry.onkelinx at inbo.be
Havenlaan 88 bus 73, 1000 Brussel
www.inbo.be

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To call in the statistician after the experiment is done may be no more
than asking him to perform a post-mortem examination: he may be able to say
what the experiment died of. ~ Sir Ronald Aylmer Fisher
The plural of anecdote is not data. ~ Roger Brinner
The combination of some data and an aching desire for an answer does not
ensure that a reasonable answer can be extracted from a given body of data.
~ John Tukey
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<https://www.inbo.be>


Op do 24 jan. 2019 om 17:30 schreef Simon POTIER <sim.potier at gmail.com>: