Question on random effects glm interpretation
Dear David, Thank you for the clarification and pointing out these R packages. We will dig into this... Best regards,
On Sun, Nov 15, 2015 at 11:59:31AM +1000, David Duffy wrote:
? On Fri, 13 Nov 2015, Thierry Onkelinx wrote:
? ? >Maybe a survival analysis is more appropriate for that kind of data. ? >> ? >>Detailed version: our data consist of daily status of a set of ? >>patients, the status being ? Infected ? or ? Not infected ?, during a ? >>variable period of time. The aim is to see what changes the infection ? >>probability. ? ? As Thierry suggested, this type of dataset (incidence of infection) can be ? modelled as a recurrent events survival analysis. These can be represented ? as in a discrete time framework as a poisson GLMM, or as Cox or parametric ? mixed effects survival models. One example might be various analyses of the ? "kidney" dataset of McGilchrist and Aisbett that is included in the BUGS ? manual. In R as: ? ? brms::kidney Infections in kidney patients ? frailtyHL::kidney Kidney Infection Data ? INLA::Kidney Kidney infection data ? survival::kidney ? ? The Markovian model appears in bivariate survival analyses covering time to ? infection and time to recovery - each may have different relevant risk ? factors - the random effect (frailty) for each individual links them ? together appropriately. You will probably also want time varying covariates. ? ? Cheers, David Duffy. ? ? ? | David Duffy (MBBS PhD) ? | email: David.Duffy at qimrberghofer.edu.au ph: INT+61+7+3362-0217 fax: -0101 ? | Genetic Epidemiology, QIMR Berghofer Institute of Medical Research ? | 300 Herston Rd, Brisbane, Queensland 4006, Australia GPG 4D0B994A
Emmanuel CURIS
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