nlmer function
Dear lme4 authors, I have studied ?Mixed models in R using the lme4 package Part 6: Nonlinear mixed models? by Douglas Bates. In this tutorial, there are some codes to fit nonlinear mixed models for Theoph data. The codes are as fallows:
Th. start <- c(lKe = -2.5, lKa = 0.5 , lCl = -3)
nm1 <- nlmer ( conc ~ SSfol (Dose , Time ,lKe , lKa , lCl) ~
+ 0+ lKe+lKa+lCl +(0+ lKe| Subject )+(0+ lKa| Subject ) + +(0+ lCl| Subject ), nAGQ =0, Theoph , + start = Th.start , verbose = TRUE ) I have 2 problems: 1. when I run these codes, I see this error: Error: unexpected '=' in: "+ +(0+ lCl| Subject ), nAGQ =0, Theoph , + start =" 2. I want to add a covariate (like age) to CL parameter. How should I modify above codes? Thanks in advance Elham Haem